LIG3 Full-Length MS Protein Standard


Product Description:

Name LIG3 Full-Length MS Protein Standard
Cat# CPFL309530
Protein Nameligase III, DNA, ATP-dependent
SymbolLIG3
SynonymsLIG2
AccessionNM_013975
Cytogenetic17q11.2-q12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW108.6 kDa
Expression TrueORF CloneRC209530
DescriptionLIG3 Full-Length MS Protein Standard (NP_039269), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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