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WWP2 Full-Length MS Protein Standard

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Product Description


NameWWP2 Full-Length MS Protein Standard
Cat#CPFL309529
Protein NameWW domain containing E3 ubiquitin protein ligase 2
SymbolWWP2
SynonymsAIP2; WWp2-like
AccessionNM_199424
Cytogenetic16q22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionWWP2 Full-Length MS Protein Standard (NP_955456), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10.

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