ASB7 Full-Length MS Protein Standard


Product Description:

Name ASB7 Full-Length MS Protein Standard
Cat# CPFL309502
Protein Nameankyrin repeat and SOCS box containing 7
SymbolASB7
SynonymsFLJ22551; FLJ25192
AccessionNM_024708
Cytogenetic15q26.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW30.5 kDa
Expression TrueORF CloneRC209502
DescriptionASB7 Full-Length MS Protein Standard (NP_078984), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.

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