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ASB7 Full-Length MS Protein Standard

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Product Description


NameASB7 Full-Length MS Protein Standard
Cat#CPFL309502
Protein Nameankyrin repeat and SOCS box containing 7
SymbolASB7
SynonymsFLJ22551; FLJ25192
AccessionNM_024708
Cytogenetic15q26.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionASB7 Full-Length MS Protein Standard (NP_078984), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.

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