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HK2 Full-Length MS Protein Standard

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Product Description


NameHK2 Full-Length MS Protein Standard
Cat#CPFL309482
Protein Namehexokinase 2
SymbolHK2
SynonymsHKII; HXK2
AccessionNM_000189
Cytogenetic2p13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHK2 Full-Length MS Protein Standard (NP_000180), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

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