CDC73 Full-Length MS Protein Standard


Product Description:

Name CDC73 Full-Length MS Protein Standard
Cat# CPFL309479
Protein Namecell division cycle 73, Paf1/RNA polymerase II complex component, homolog
SymbolCDC73
SynonymsC1orf28; FIHP; HPTJT; HRPT1; HRPT2; HYX
AccessionNM_024529
Cytogenetic1q25
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW60.4 kDa
Expression TrueORF CloneRC209479
DescriptionCDC73 Full-Length MS Protein Standard (NP_078805), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3 mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

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