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COL6A2 Full-Length MS Protein Standard

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Product Description


NameCOL6A2 Full-Length MS Protein Standard
Cat#CPFL309476
Protein Namecollagen, type VI, alpha 2
SymbolCOL6A2
SynonymsPP3610
AccessionNM_001849
Cytogenetic21q22.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCOL6A2 Full-Length MS Protein Standard (NP_001840), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.

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