VPS11 Full-Length MS Protein Standard


Product Description:

Name VPS11 Full-Length MS Protein Standard
Cat# CPFL309474
Protein Namevacuolar protein sorting 11 homolog (S. cerevisiae)
SymbolVPS11
SynonymsEND1; hVPS11; PEP5; RNF108
AccessionNM_021729
Cytogenetic11q23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW107.6 kDa
Expression TrueORF CloneRC209474
DescriptionVPS11 Full-Length MS Protein Standard (NP_068375), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants.

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