ENPP1 Full-Length MS Protein Standard


Product Description:

Name ENPP1 Full-Length MS Protein Standard
Cat# CPFL309222
Protein Nameectonucleotide pyrophosphatase/phosphodiesterase 1
SymbolENPP1
SynonymsARHR2; COLED; M6S1; NPP1; NPPS; PC-1; PCA1; PDNP1
AccessionNM_006208
Cytogenetic6q22-q23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW99.8 kDa
Expression TrueORF CloneRC209222
DescriptionENPP1 Full-Length MS Protein Standard (NP_006199), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5 triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with idiopathic infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.

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