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BCL3 Full-Length MS Protein Standard

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Product Description


NameBCL3 Full-Length MS Protein Standard
Cat#CPFL309116
Protein NameB-cell CLL/lymphoma 3
SymbolBCL3
SynonymsBCL4; D19S37
AccessionNM_005178
Cytogenetic19q13.1-q13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionBCL3 Full-Length MS Protein Standard (NP_005169), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.

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