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ADARB1 Full-Length MS Protein Standard

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Product Description


NameADARB1 Full-Length MS Protein Standard
Cat#CPFL309073
Protein Nameadenosine deaminase, RNA-specific, B1
SymbolADARB1
SynonymsADAR2; DRABA2; DRADA2; RED1
AccessionNM_001112
Cytogenetic21q22.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionADARB1 Full-Length MS Protein Standard (NP_001103), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.

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