KREMEN1 Full-Length MS Protein Standard


Product Description:

Name KREMEN1 Full-Length MS Protein Standard
Cat# CPFL308991
Protein Namekringle containing transmembrane protein 1
SymbolKREMEN1
SynonymsFLJ31863; KREMEM1; KREMEN; KRM1; KREMEM1; KREMEN; KRM1; OTTHUMP00000028977; kringle-coding gene marking the eye and the nose; kringle-containing transmembrane protein 1; kringle containing transmembrane protein 1
AccessionNM_001039571
Cytogenetic22q12.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW48.3 kDa
Expression TrueORF CloneRC208991
DescriptionKREMEN1 Full-Length MS Protein Standard (NP_001034660), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

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