CCDC50 Full-Length MS Protein Standard


Product Description:

Name CCDC50 Full-Length MS Protein Standard
Cat# CPFL308965
Protein Namecoiled-coil domain containing 50
SymbolCCDC50
SynonymsC3orf6; DFNA44; YMER
AccessionNM_174908
Cytogenetic3q28
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW35.6 kDa
Expression TrueORF CloneRC208965
DescriptionCCDC50 Full-Length MS Protein Standard (NP_777568), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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