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KNG1 Full-Length MS Protein Standard

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Product Description


NameKNG1 Full-Length MS Protein Standard
Cat#CPFL308879
Protein NameKininogen Heavy Chain
SymbolKNG1
SynonymsBDK; BK; KNG
AccessionNM_000893
Cytogenetic3q27
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionKNG1 Full-Length MS Protein Standard (NP_000884), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

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