| Name | KNG1 Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL308879 |
| Protein Name | Kininogen Heavy Chain |
| Symbol | KNG1 |
| Synonyms | BDK; BK; KNG |
| Accession | NM_000893 |
| Cytogenetic | 3q27 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 47.7 kDa |
| Expression TrueORF Clone | RC208879 |
| Description | KNG1 Full-Length MS Protein Standard (NP_000884), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene. |
| Cat# | Protein Sequence | Price |
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