GALNS Full-Length MS Protein Standard


Product Description:

Name GALNS Full-Length MS Protein Standard
Cat# CPFL308708
Protein Namegalactosamine (N-acetyl)-6-sulfate sulfatase
SymbolGALNS
SynonymsGalN6S; GALNAC6S; GAS; MPS4A
AccessionNM_000512
Cytogenetic16q24.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW55.4 kDa
Expression TrueORF CloneRC208708
DescriptionGALNS Full-Length MS Protein Standard (NP_000503), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.

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