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YWHAQ Full-Length MS Protein Standard

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Product Description


NameYWHAQ Full-Length MS Protein Standard
Cat#CPFL308646
Protein Nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
SymbolYWHAQ
Synonyms14-3-3; 1C5; HS1
AccessionNM_006826
Cytogenetic2p25.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionYWHAQ Full-Length MS Protein Standard (NP_006817), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5 UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

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