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UBE2K Full-Length MS Protein Standard

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Product Description


NameUBE2K Full-Length MS Protein Standard
Cat#CPFL308645
Protein Nameubiquitin-conjugating enzyme E2K
SymbolUBE2K
SynonymsE2-25K; HIP2; HYPG; LIG; UBC1
AccessionNM_005339
Cytogenetic4p14
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionUBE2K Full-Length MS Protein Standard (NP_005330), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntingtons disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

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