LRRC8A Full-Length MS Protein Standard


Product Description:

Name LRRC8A Full-Length MS Protein Standard
Cat# CPFL308632
Protein Nameleucine rich repeat containing 8A
SymbolLRRC8A
SynonymsAGM5; LRRC8; SWELL1
AccessionNM_019594
Cytogenetic9q34.11
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW94 kDa
Expression TrueORF CloneRC208632
DescriptionLRRC8A Full-Length MS Protein Standard (NP_062540), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

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