DNM2 Full-Length MS Protein Standard


Product Description:

Name DNM2 Full-Length MS Protein Standard
Cat# CPFL308525
Protein Namedynamin 2
SymbolDNM2
SynonymsCMT2M; CMTDI1; CMTDIB; DI-CMTB; DYN2; DYNII; LCCS5
AccessionNM_004945
Cytogenetic19p13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW97.5 kDa
Expression TrueORF CloneRC208525
DescriptionDNM2 Full-Length MS Protein Standard (NP_004936), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

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