SEC63 Full-Length MS Protein Standard


Product Description:

Name SEC63 Full-Length MS Protein Standard
Cat# CPFL308436
Protein NameSEC63 homolog (S. cerevisiae)
SymbolSEC63
SynonymsDNAJC23; ERdj2; PRO2507; SEC63L
AccessionNM_007214
Cytogenetic6q21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW87.8 kDa
Expression TrueORF CloneRC208436
DescriptionSEC63 Full-Length MS Protein Standard (NP_009145), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

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