COA5 Full-Length MS Protein Standard


Product Description:

Name COA5 Full-Length MS Protein Standard
Cat# CPFL308299
Protein Namecytochrome C oxidase assembly factor 5
SymbolCOA5
Synonyms6330578E17Rik; C2orf64; Pet191
AccessionNM_001008215
Cytogenetic2q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW8.2 kDa
Expression TrueORF CloneRC208299
DescriptionC2orf64 Full-Length MS Protein Standard (NP_001008216), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes an ortholog of yeast Pet191, which in yeast is a subunit of a large oligomeric complex associated with the mitochondrial inner membrane, and required for the assembly of the cytochrome c oxidase complex. Mutations in this gene are associated with mitochondrial complex IV deficiency, a disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to a severe disease affecting several tissues and organs.

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