GFM1 Full-Length MS Protein Standard


Product Description:

Name GFM1 Full-Length MS Protein Standard
Cat# CPFL308239
Protein NameG elongation factor, mitochondrial 1
SymbolGFM1
SynonymsCOXPD1; EFG; EFG1; EFGM; EGF1; GFM; hEFG1
AccessionNM_024996
Cytogenetic3q25
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW83.3 kDa
Expression TrueORF CloneRC208239
DescriptionGFM1 Full-Length MS Protein Standard (NP_079272), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.

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