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OLIG2 Full-Length MS Protein Standard

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Product Description


NameOLIG2 Full-Length MS Protein Standard
Cat#CPFL308209
Protein Nameoligodendrocyte lineage transcription factor 2
SymbolOLIG2
SynonymsBHLHB1; bHLHe19; OLIGO2; PRKCBP2; RACK17
AccessionNM_005806
Cytogenetic21q22.11
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionOLIG2 Full-Length MS Protein Standard (NP_005797), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.

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