GUCY1B3 Full-Length MS Protein Standard


Product Description:

Name GUCY1B3 Full-Length MS Protein Standard
Cat# CPFL308205
Protein NameGuanylate cyclase 1, soluble, beta 3
SymbolGUCY1B3
SynonymsGC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B1
AccessionNM_000857
Cytogenetic4q31.3-q33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW70.3 kDa
Expression TrueORF CloneRC208205
DescriptionGUCY1B3 Full-Length MS Protein Standard (NP_000848), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.

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