ETV6 Full-Length MS Protein Standard


Product Description:

Name ETV6 Full-Length MS Protein Standard
Cat# CPFL308185
Protein Nameets variant 6
SymbolETV6
SynonymsTEL; TEL/ABL; THC5
AccessionNM_001987
Cytogenetic12p13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW52.8 kDa
Expression TrueORF CloneRC208185
DescriptionETV6 Full-Length MS Protein Standard (NP_001978), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

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