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MPI Full-Length MS Protein Standard

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Product Description


NameMPI Full-Length MS Protein Standard
Cat#CPFL308134
Protein Namemannose phosphate isomerase
SymbolMPI
SynonymsCDG1B; PMI; PMI1
AccessionNM_002435
Cytogenetic15q24.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMPI Full-Length MS Protein Standard (NP_002426), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants.

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