CRKL Full-Length MS Protein Standard


Product Description:

Name CRKL Full-Length MS Protein Standard
Cat# CPFL308129
Protein Namev-crk sarcoma virus CT10 oncogene homolog (avian)-like
SymbolCRKL
Synonymsv-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like
AccessionNM_005207
Cytogenetic22q11.21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW33.6 kDa
Expression TrueORF CloneRC208129
DescriptionCRKL Full-Length MS Protein Standard (NP_005198), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

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