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RP2 Full-Length MS Protein Standard

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Product Description


NameRP2 Full-Length MS Protein Standard
Cat#CPFL308124
Protein Nameretinitis pigmentosa 2 (X-linked recessive)
SymbolRP2
SynonymsDELXp11.3; NM23-H10; NME10; TBCCD2; XRP2
AccessionNM_006915
CytogeneticXp11.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionRP2 Full-Length MS Protein Standard (NP_008846), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death )

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