UBTF Full-Length MS Protein Standard


Product Description:

Name UBTF Full-Length MS Protein Standard
Cat# CPFL308047
Protein Nameupstream binding transcription factor, RNA polymerase I
SymbolUBTF
SynonymsNOR-90; UBF; UBF-1; UBF1; UBF2
AccessionNM_001076683
Cytogenetic17q21.31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW84.8 kDa
Expression TrueORF CloneRC208047
DescriptionUBTF Full-Length MS Protein Standard (NP_001070151), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

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