ACSL3 Full-Length MS Protein Standard


Product Description:

Name ACSL3 Full-Length MS Protein Standard
Cat# CPFL308032
Protein Nameacyl-CoA synthetase long-chain family member 3
SymbolACSL3
SynonymsACS3; FACL3; PRO2194
AccessionNM_004457
Cytogenetic2q34-q35
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW80.2 kDa
Expression TrueORF CloneRC208032
DescriptionACSL3 Full-Length MS Protein Standard (NP_004448), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.

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