TBXAS1 Full-Length MS Protein Standard


Product Description:

Name TBXAS1 Full-Length MS Protein Standard
Cat# CPFL308028
Protein Namethromboxane A synthase 1 (platelet)
SymbolTBXAS1
SynonymsBDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS
AccessionNM_001061
Cytogenetic7q34-q35
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW60.5 kDa
Expression TrueORF CloneRC208028
DescriptionTBXAS1 Full-Length MS Protein Standard (NP_001052), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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