UBE2R2 Full-Length MS Protein Standard


Product Description:

Name UBE2R2 Full-Length MS Protein Standard
Cat# CPFL307977
Protein Nameubiquitin-conjugating enzyme E2R 2
SymbolUBE2R2
SynonymsCDC34B; E2-CDC34B; UBC3B
AccessionNM_017811
Cytogenetic9p13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW27 kDa
Expression TrueORF CloneRC207977
DescriptionUBE2R2 Full-Length MS Protein Standard (NP_060281), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

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