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RCHY1 Full-Length MS Protein Standard


Product Description

NameRCHY1 Full-Length MS Protein Standard
Protein Namering finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
SynonymsARNIP; CHIMP; PIRH2; PRO1996; RNF199; ZCHY; ZNF363
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW29.9 kDa
Expression TrueORF CloneRC207970
DescriptionRCHY1 Full-Length MS Protein Standard (NP_056251), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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