Name | EHHADH Full-Length MS Protein Standard |
Cat# | CPFL307928 |
Protein Name | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
Symbol | EHHADH |
Synonyms | ECHD; FRTS3; L-PBE; LBFP; LBP; PBFE |
Accession | NM_001966 |
Cytogenetic | 3q26.3-q28 |
Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Expression Host | Human HEK293 cells |
Predicted MW | 79.3 kDa |
Expression TrueORF Clone | RC207928 |
Description | EHHADH Full-Length MS Protein Standard (NP_001957), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. |
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