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EHHADH Full-Length MS Protein Standard

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Product Description


NameEHHADH Full-Length MS Protein Standard
Cat#CPFL307928
Protein Nameenoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
SymbolEHHADH
SynonymsECHD; FRTS3; L-PBE; LBFP; LBP; PBFE
AccessionNM_001966
Cytogenetic3q26.3-q28
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionEHHADH Full-Length MS Protein Standard (NP_001957), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene.

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