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A2M Full-Length MS Protein Standard

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Product Description


NameA2M Full-Length MS Protein Standard
Cat#CPFL307905
Protein Namealpha-2-macroglobulin
SymbolA2M
SynonymsA2MD; CPAMD5; FWP007; S863-7
AccessionNM_000014
Cytogenetic12p13.31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionA2M Full-Length MS Protein Standard (NP_000005), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.

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