TTL Full-Length MS Protein Standard


Product Description:

Name TTL Full-Length MS Protein Standard
Cat# CPFL307805
Protein Nametubulin tyrosine ligase
SymbolTTL
SynonymsMGC46235
AccessionNM_153712
Cytogenetic2q13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW43 kDa
Expression TrueORF CloneRC207805
DescriptionTTL Full-Length MS Protein Standard (NP_714923), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 )

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