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PDE4A Full-Length MS Protein Standard

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Product Description


NamePDE4A Full-Length MS Protein Standard
Cat#CPFL307765
Protein NamePDE4A phosphodiesterase 4A, cAMP-specific
SymbolPDE4A
SynonymsDPDE2; PDE4; PDE46
AccessionNM_006202
Cytogenetic19p13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionPDE4A Full-Length MS Protein Standard (NP_006193), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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