CLCA2 Full-Length MS Protein Standard


Product Description:

Name CLCA2 Full-Length MS Protein Standard
Cat# CPFL307731
Protein Namechloride channel accessory 2
SymbolCLCA2
SynonymsCACC; CaCC-3; CACC3; CLCRG2
AccessionNM_006536
Cytogenetic1p22.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW100.6 kDa
Expression TrueORF CloneRC207731
DescriptionCLCA2 Full-Length MS Protein Standard (NP_006527), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer.

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