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IKBKAP Full-Length MS Protein Standard


Product Description

NameIKBKAP Full-Length MS Protein Standard
Protein Nameinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
SynonymsDYS; ELP1; FD; IKAP; IKI3; TOT1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW150.1 kDa
Expression TrueORF CloneRC207686
DescriptionIKBKAP Full-Length MS Protein Standard (NP_003631), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia.

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