TLK1 Full-Length MS Protein Standard


Product Description:

Name TLK1 Full-Length MS Protein Standard
Cat# CPFL307653
Protein Nametousled-like kinase 1
SymbolTLK1
SynonymsPKU-beta
AccessionNM_012290
Cytogenetic2q31.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW86.5 kDa
Expression TrueORF CloneRC207653
DescriptionTLK1 Full-Length MS Protein Standard (NP_036422), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.

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