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DOK2 Full-Length MS Protein Standard

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Product Description


NameDOK2 Full-Length MS Protein Standard
Cat#CPFL307621
Protein Namedocking protein 2, 56kDa
SymbolDOK2
Synonymsp56DOK; p56dok-2
AccessionNM_003974
Cytogenetic8p21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionDOK2 Full-Length MS Protein Standard (NP_003965), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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