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GPNMB Full-Length MS Protein Standard

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Product Description


NameGPNMB Full-Length MS Protein Standard
Cat#CPFL307615
Protein Nameglycoprotein (transmembrane) nmb
SymbolGPNMB
SynonymsHGFIN; NMB
AccessionNM_001005340
Cytogenetic7p15
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGPNMB Full-Length MS Protein Standard (NP_001005340), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

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