APLNR Full-Length MS Protein Standard


Product Description:

Name APLNR Full-Length MS Protein Standard
Cat# CPFL307576
Protein NameAPLNR apelin receptor
SymbolAPLNR
SynonymsAGTRL1; APJ; APJR; HG11
AccessionNM_005161
Cytogenetic11q12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW42.5 kDa
Expression TrueORF CloneRC207576
DescriptionAPLNR Full-Length MS Protein Standard (NP_005152), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

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