RACGAP1 Full-Length MS Protein Standard


Product Description:

Name RACGAP1 Full-Length MS Protein Standard
Cat# CPFL307542
Protein NameRac GTPase activating protein 1
SymbolRACGAP1
SynonymsCYK4; HsCYK-4; ID-GAP; MgcRacGAP
AccessionNM_013277
Cytogenetic12q13.12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW70.8 kDa
Expression TrueORF CloneRC207542
DescriptionRACGAP1 Full-Length MS Protein Standard (NP_037409), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene.

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