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MARCH2 Full-Length MS Protein Standard

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Product Description


NameMARCH2 Full-Length MS Protein Standard
Cat#CPFL307517
Protein Namemitochondrial amidoxime reducing component 2
SymbolMARCH2
SynonymsHSPC240; MARCH-II; RNF172
AccessionNM_016496
Cytogenetic19p13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMARCH2 Full-Length MS Protein Standard (NP_057580), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 )

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