KCNIP4 Full-Length MS Protein Standard


Product Description:

Name KCNIP4 Full-Length MS Protein Standard
Cat# CPFL307464
Protein NameKCNIP4 Kv channel interacting protein 4
SymbolKCNIP4
SynonymsCALP; KCHIP4
AccessionNM_001035004
Cytogenetic4p15.32
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW21.8 kDa
Expression TrueORF CloneRC207464
DescriptionKCNIP4 Full-Length MS Protein Standard (NP_001030176), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

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