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KCNAB1 Full-Length MS Protein Standard

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Product Description


NameKCNAB1 Full-Length MS Protein Standard
Cat#CPFL307384
Protein Namepotassium voltage-gated channel, shaker-related subfamily, beta member 1
SymbolKCNAB1
SynonymsAKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3
AccessionNM_172159
Cytogenetic3q26.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionKCNAB1 Full-Length MS Protein Standard (NP_751891), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits.

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