CRY2 Full-Length MS Protein Standard


Product Description:

Name CRY2 Full-Length MS Protein Standard
Cat# CPFL307337
Protein Namecryptochrome 2 (photolyase-like)
SymbolCRY2
SynonymsHCRY2; PHLL2
AccessionNM_021117
Cytogenetic11p11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW66.8 kDa
Expression TrueORF CloneRC207337
DescriptionCRY2 Full-Length MS Protein Standard (NP_066940), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.

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