UBE2D2 Full-Length MS Protein Standard


Product Description:

Name UBE2D2 Full-Length MS Protein Standard
Cat# CPFL307283
Protein Nameubiquitin-conjugating enzyme E2D 2
SymbolUBE2D2
SynonymsE2(17)KB2; PUBC1; UBC4; UBC4/5; UBCH4; UBCH5B
AccessionNM_181838
Cytogenetic5q31.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW13.5 kDa
Expression TrueORF CloneRC207283
DescriptionUBE2D2 Full-Length MS Protein Standard (NP_862821), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene.

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