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GCLM Full-Length MS Protein Standard

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Product Description


NameGCLM Full-Length MS Protein Standard
Cat#CPFL307224
Protein Nameglutamate-cysteine ligase, modifier subunit
SymbolGCLM
SynonymsGLCLR
AccessionNM_002061
Cytogenetic1p22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGCLM Full-Length MS Protein Standard (NP_002052), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

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