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IMPDH1 Full-Length MS Protein Standard

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Product Description


NameIMPDH1 Full-Length MS Protein Standard
Cat#CPFL307118
Protein NameIMP (inosine 5-monophosphate) dehydrogenase 1
SymbolIMPDH1
SynonymsIMPD; IMPD1; LCA11; RP10; sWSS2608
AccessionNM_183243
Cytogenetic7q31.3-q32
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionIMPDH1 Full-Length MS Protein Standard (NP_899066), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

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